Endocrine Abstracts

Blackground: Parathyroid carcinoma is a malignant neoplasm affecting 0.5 to 5.0% of all patients suffering from primary hyperparathyroidism. This cancer continues to cause challenges for diagnosis and treatment because of its rarity, overlapping features with benign parathyroid disease.Case report: 50 years-old-woman, without relevant previous history. She begins to present asthenia, weakness of lower limbs, arthralgias, cramps and appearance of a painfu...

Introduction: Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with an increased risk of adverse outcomes, so pregnancy planning in order to achieve an optimal glycemic control is essential. This control has been made possible, in part, by the widespread use of insulin analogues, especially the long-acting ones, glargine and detemir. Insulin degludec, an ultra-long-acting insulin is not currently approved for pregnant women due to the lack of randomized co...

Introduction: Adrenal tumors are common tumors with a prevalence of around 3% in a population over the age of 50 years. In contrast, adrenocortical carcinoma (ACC) is a rare malignancy (incidence 1–2 per 1 million population) with a heterogeneous presentation and a variable but generally bad prognosis. Patients present with evidence of adrenal steroid hormone excess in approximately 60% of cases.Case report: A 49-year-old woman with symptoms of faci...

Introduction: Type 1 diabetes mellitus (T1DM) is considered, in general, a disease of children and young adults with normal body mass index (BMI), linked to a genetic susceptibility based on autoimmunity. However, we know that it can be diagnosed at any age and we must differentiate it from type 2 diabetes mellitus.Objetives: To investigate the phenotypic characteristics and the presence of specific autoimmunity in T1DM patients diagnosed in our hospital...

Introduction: Squamous cell thyroid carcinoma is a very rare malignant epithelial tumour. It presents as rapid growth cervical mass, may affect neighbour structures and sometimes metastasizes other parts of the body. It’s often associated with previous goiter history and occasionally with autoimmune thyroiditis. It can appear pure, as a component of undifferentiated carcinoma, or combined with differentiated carcinoma areas (papillary or follicular).<p class="abstext"...

Introduction: New treatments of diabetes improve global metabolic status beyond glycemic control and achieve weight reduction in many patients.Case reports: We described four case reports to show GLP-1 agonists and dapaglifozin effects on metabolism and weight in patients with type 2 diabetes and obesity.Case 1 (Liraglutide): A 48-year-old man, hypertension, type 2 diabetes and extreme obesity. Baseline visit: treatment enalapril 2...

Introduction: H. pylori infection has been related with extragastric diseases such as type 2 diabetes.Aim: to evaluate changes in carbohydrate metabolism induced by 75g oral glucose tolerance test (OGTT), before and after antibiotic eradication treatment in patients colonized by H. pylori compared to healthy controls.Materials and methods: A prospective case-control study. Biochemical parameters, carbohydrate profile, ghrelin and G...

Introduction: H. pylori infection has been related with diseases such as type 2 diabetes and metabolic syndrome.Objective: To evaluate changes in carbohydrates metabolism, lipid profile and intake regulating hormones induced by 75 g oral glucose tolerance test (OGTT), before and after antibiotic eradication treatment in patients colonized by H. pylori.Materials and methods: A prospective study of 40 non-diabetics patients were perf...